Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg)

Description

Fragment 176-191 & CJC-1295 & Ipamorelin Peptide Blend: Growth Hormone Boosting Synergy

The Fragment 176-191, CJC-1295, and Ipamorelin peptide blend is a powerful combination designed to promote natural growth hormone (GH) secretion, supporting a range of physiological benefits, including enhanced fat metabolism, increased lean mass, improved sleep quality, and better intestinal and cardiac function.

CJC-1295 Peptide: Growth Hormone-Releasing Hormone Analog

CJC-1295 is a synthetic peptide consisting of 29 amino acids. It works by activating the Growth Hormone-Releasing Hormone (GHRH) receptors in the pituitary gland, mimicking the action of natural GHRH. Modified with a Drug Affinity Complex (DAC), CJC-1295 offers extended pharmacokinetics, enhancing its effectiveness and duration of action.

Ipamorelin Peptide: Growth Hormone Secretagogue

Ipamorelin, a synthetic pentapeptide, functions as a growth hormone secretagogue (GHS), closely mimicking the natural hunger hormone ghrelin. It activates the Ghrelin Receptors (GHS-R1a) in the anterior pituitary gland, promoting the release of human growth hormone (hGH) and supporting natural GH production. You may also be interested in our related research peptides, including Tripeptide, Sermorelin Peptide, Hexarelin, Melanotan 1, Oxytocin Peptide, Snap 8 Peptide, Pinealon, Kisspeptin 10 mg, VIP Peptide, and ARA 290 Peptide.

Fragment 176-191: Fat-Burning and Thermogenesis

The Fragment 176-191 peptide, derived from the larger human growth hormone (hGH), is made up of 15 amino acids. It targets the beta-3 adrenergic receptors (ADRB3) in adipose tissue, stimulating fat burning and potentially increasing thermogenesis in skeletal muscle. This peptide may play a key role in weight loss and fat reduction.

Synergistic Growth Hormone Regulation

Together, this peptide blend may act synergistically to stimulate the pituitary gland, potentially enhancing and regulating growth hormone levels. By promoting GH secretion and improving metabolic functions, this combination helps maintain balanced GH concentrations, contributing to better overall health and wellness.

Chemical Makeup^(1)(2)(3)

Molecular formula

• Fragment 176-191: C₇₈H₁₂₅N₂₃O₂₃S₂
• CJC-1295 (Mod GRF 1-29): C₁₅₂H₂₅₂N₄₄O₄₂
• Ipamorelin: C₃₈H₄₉N₉O₅

Molecular weight

• Fragment 176-191: 1817.12 g/mol
• CJC-1295 (Mod GRF 1-29): 3367.9 g/mol
• Ipamorelin: 711.8 g/mol

Other known titles

• Fragment 176-191: AOD 9604, GH (hGH) lipolytic fragment, Somatostatin (177-191), tyrosyl
• CJC-1295: Mod GRF 1-29, CJC-1295 without DAC
• Ipamorelin Ipamorelin Acetate, IPA

Research and Clinical Studies on the Fragment 176-191, CJC-1295, and Ipamorelin Peptide Blend

Growth Hormone Boosting Potential

The Fragment 176-191, CJC-1295, and Ipamorelin peptide blend works synergistically to promote growth hormone (hGH) secretion and boost metabolic functions. While Fragment 176-191 mimics the function of hGH, CJC-1295 and Ipamorelin enhance hGH synthesis itself, increasing the natural production of growth hormone in the body.

CJC-1295 and Growth Hormone Synthesis

CJC-1295, a synthetic analog of the Growth Hormone-Releasing Hormone (GHRH), has been shown to have significant hGH-boosting effects in multiple clinical studies. One phase-1 clinical trial(4) enrolled subjects aged 20 to 40 years and divided them into two groups: one received a saline placebo, and the other was given CJC-1295. After treatment, the CJC-1295 group showed a 7.5-fold increase in growth hormone levels, with the elevated levels persisting for up to 7 days after discontinuation. Another study(5) on male subjects aged 20 to 60 years demonstrated that CJC-1295 could increase growth hormone levels by up to 10 times, depending on the concentration administered. These results suggest that CJC-1295 significantly stimulates hGH release, contributing to increased IGF-1 production and various health benefits, including improved muscle growth, fat metabolism, and overall vitality.

Ipamorelin and hGH Secretion

Ipamorelin, a synthetic pentapeptide, is also known for its ability to stimulate hGH release. In one clinical study(6), a single dose of Ipamorelin was shown to increase hGH levels by over 60-fold, compared to placebo. This marked enhancement in hGH secretion supports the peptide’s potential as a growth hormone secretagogue, promoting the natural release of growth hormone and contributing to overall metabolic health.

Lipolytic (Fat-Burning) Effects

The Fragment 176-191, CJC-1295, and Ipamorelin peptide blend has also been studied for its lipolytic (fat-burning) effects, with promising results. A clinical trial in 2004(7) explored the fat-reducing potential of Fragment 176-191, enrolling 300 subjects over a 12-week period. The subjects were divided into six groups, with one receiving a saline placebo and the rest receiving various concentrations of the peptide blend. The group receiving the lowest concentration of the peptide showed a notable reduction in body weight – up to 2.8 kilograms – along with improvements in cholesterol levels and glucose tolerance. Researchers concluded that the peptide blend led to competitive weight loss and accompanying health benefits, suggesting its potential as an effective weight loss and metabolic enhancement tool.